are noted in recent years cases when бабезиоз at dogs proceeds without characteristic clinical signs and without a lethal outcome. However, at a research of dabs of blood painted according to Romanovsky-Gimz babeziya are found. It indicates carriage of the activator. The diagnosis is, as a rule, made absolutely other: from poisoning to cirrhosis. The babezionositelstvo among homeless city dogs is of special interest.
Existence of freely circulating Babesia canis activator in population of homeless dogs is quite serious link in an epizootic chain of a disease. It is possible to assume that these animals are the tank of a parasite promoting his preservation. Thus, it is possible to draw a conclusion that in population of homeless dogs there was a steady parasite owner system. However, at this stage it is impossible to define, it happened owing to easing of pathogenic and virulent Babesia canis properties or at the expense of the increased resistance of an organism of dogs to this activator.
Babezioz of dogs proceeds сверхостро (immediately), sharply and chronically. The incubatory period at infection with a natural strain to last 13-21 days, at experimental infection – from 2 to 7 days.
At a supersharp course of disease of a dog perish without manifestation of clinical signs. Defeat of an organism of a dog of Babesia canis at the sharp course of a disease causes fever, the sharp temperature increase of a body up to 41-42 °C keeping within 2-3 days with its subsequent fast falling to and below norm (30-35 °C). At young dogs at whom death comes very quickly temperature increase at the beginning of a disease can be absent.
At dogs are noted lack of appetite, a depression, depression, low threadlike pulse (to 120-160 beats per minute), further becomes arrhythmic. The warm push is strengthened. The breath which is speeded up (till 36-48 in a minute) and complicated, at young dogs often with groan. At a palpation of the left belly wall (behind a costal arch) find the increased spleen.
Mucous membranes of a mouth and a conjunctiva are anemic
, zheltushna. Intensive destruction of erythrocytes is followed by nephrite. The gait becomes complicated, the gemoglobinuriya appears. The disease proceeds from 2 to 5 days, 10-11 days are more rare, it is frequent from the death (N.A. Kazakov, 1982).
In most cases observe hemolytic anemia owing to mass destruction of erythrocytes, a gemoglobinuriya (at the same time urine becomes reddish or coffee color), a bilirubinemiya, yellowness, intoxication, damage of the central nervous system. Defeat of integuments of type of a small tortoiseshell, hemorrhagic spots is sometimes noted. Muscular and articulate pains are often observed. The gepatomegaliya and a splenomegaliya is often observed. Agglutination of erythrocytes in brain capillaries can be observed. In the absence of the timely help animals, as a rule, perish for 3-5 day of a disease.
often observe the Chronic current at the dogs who earlier had babeziozy and also at animals with the increased resistance of an organism. This form of a disease is characterized by development of anemia, muscle weakness and exhaustion. At sick animals temperature increase to 40-41 °C in the first days of a disease is also noted. Further temperature decreases to norm (on average, 38-39 °C). Animals sluggish, the appetite is reduced. Quite often there are ponosa with bright yellow coloring of fecal masses. Duration of a disease is 3-8 weeks. The disease, as a rule, comes to an end with gradual recovery. (N.A. Kazakov, 1982 A.I. Yatusevich, V.T. Zablotsky, 1995).
Quite often in scientific literature can meet data on parazitotsenoza: бабезиоз, anaplasmosis, rickettsial disease, leptospirosis, etc. (A.I. Yatusevich, etc., 2006 N.V. Molotov, 2007, etc.). According to P. Seneviratna (1965), from 132 dogs examined by it on secondary infections and invasions of 28 dogs had the parasitic disease caused by Ancylostoma caninum 8 – filariasis 6 – other infections and invasions had leptospirosis of 15 dogs.
the Fallen dogs are exhausted. Mucous membranes, hypodermic cellulose and serous covers of a zheltushna. On mucous intestines sometimes there are dot or striate hemorrhages. The spleen is increased, the pulp is softened, from bright red till dark cherry color, a surface hilly. The liver is increased, light-cherry, is more rare than brown color, the parenchyma is condensed. The gall bladder is crowded with bile of orange color.
of the Kidney are increased, edematous, hyperemic, the capsule easily is removed, a cortical layer of dark red color, brain – red. The bladder is filled with urine of red or coffee color, on a mucous membrane dot or striate hemorrhages. A cardiac muscle of dark red color, under Epi - and endokardy striate hemorrhages. Cavities of heart contain the "varnish" not turned blood.
At a supersharp current are found in the fallen animals the following changes. Mucous membranes have light lemon yellowness. Blood in large vessels dense, dark red. In many bodies accurate dot hemorrhages are noted: in a timus, a pancreas, under epikardy, in a cortical layer of kidneys, under a pleura, in lymph nodes, on tops of folds of a stomach. The external and internal lymph nodes which bulked up, damp, gray, with noticeable follicles in a cortical zone. The spleen has the dense pulp giving moderate scrape. The myocardium is pale gray, flabby. Kidneys also have flabby consistence. The capsule easily is removed. In a liver symptoms of proteinaceous dystrophy are found. Lungs have intensive-red color, dense consistence, in a trachea often find dense red foam. In a brain the smoothness of crinkles is noted. In a duodenum and a front part lean the mucous membrane which reddened, friable. In other departments of intestines the surface of mucous is covered with moderate amount of dense gray slime. Solitary follicles and peyerova of a plaque large, accurate, are densely located in the thickness of intestines. As feature it should be noted lack of a gemosideroz – an indicator of the strengthened disintegration of erythrocytes (V.L. Lebedeva, 1992).